Hydrogen Peroxide → HCID 67852818, compound

HRID 1587695Notes

Reaction equation

HRID 1587695 reaction equation
[CH2:1]([O:7][C:8]1[N:13]=[C:12]([CH3:14])[CH:11]=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[OH:15]O>C(O)(=O)C>[CH2:1]([O:7][C:8]1[CH:9]=[CH:10][CH:11]=[C:12]([CH3:14])[N+:13]=1[O-:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 784Hydrogen Peroxide2×HCID 19756143HCID 19756143, compound

Product 1

HCID 67852818HCID 67852818, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 8.60 g (44 mmol) of 6-hexyloxy-α-picoline dissolved in 43 ml of acetic acid was added 6.4 ml of hydrogen peroxide, the mixture was stirred at 70° to 80° C. for 3 hours, further 4 ml of hydrogen peroxide was added, and the mixture was stirred at the same temperature for 3 hours. After concentration under a reduced pressure to a half amount, water was added and the mixture concentrated under a reduced pressure (repeated for three times). A crude in an amount of 5.50 g was obtained.

Workup

  1. stirringthe mixture was stirred at the same temperature for 3 hours
  2. concentrationAfter concentration under a reduced pressure to a half amount, water
  3. additionwas added
  4. concentrationthe mixture concentrated under a reduced pressure (repeated for three times)
  5. customA crude in an amount of 5.50 g was obtained

Sources & evidence

ORD record
ord-da986bd0ba7f4b93ac5f853813971f3a
Source dataset
uspto-grants-1993_06
Patent number
US05219847

Reaction notes

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