Water → Tert-butyl 4-[3-(propionylamino)phenyl]-1-piperidinecarboxylate

HRID 158777Notes

Reaction equation

HRID 158777 reaction equation
[C:1]([CH2:2][CH3:3])(=[O:4])[Cl:5].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[NH2:6][c:7]1[cH:8][c:9]([CH:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)[cH:10][cH:11][cH:12]1.[OH2:26]>>[C:1]([CH2:2][CH3:3])(=[O:4])[NH:6][c:7]1[cH:8][c:9]([CH:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)[cH:10][cH:11][cH:12]1

Participants

5

Reactant 4

HCID 962WaterHCID 8028TetrahydrofuranHCID 62324Propionyl chlorideHCID 22049268tert-Butyl 4-(3-aminophenyl)piperidine-1-carboxylate

Product 1

HCID 22049473Tert-butyl 4-[3-(propionylamino)phenyl]-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-e151fe9bbaad43b7bc61d633cfc3a214
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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