HCID 14477506, compound → HCID 14477508, compound

HRID 1587989Notes

Reaction equation

HRID 1587989 reaction equation
[NH:1]([C:32]([O:34][C:35]([CH3:38])([CH3:37])[CH3:36])=[O:33])[C@H:2]([C:7]([NH:9][C@H:10]([C:15]([N:17]1[CH2:31][CH2:30][CH2:29][C@H:18]1[C:19]([O:21]CC1C=CC=CC=1)=[O:20])=[O:16])[CH2:11][C:12](=[O:14])[NH2:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]>[Pd].CN(C=O)C>[NH:1]([C:32]([O:34][C:35]([CH3:38])([CH3:37])[CH3:36])=[O:33])[C@H:2]([C:7]([NH:9][C@H:10]([C:15]([N:17]1[CH2:31][CH2:30][CH2:29][C@H:18]1[C:19]([OH:21])=[O:20])=[O:16])[CH2:11][C:12](=[O:14])[NH2:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]

Participants

4

Reactant 1

HCID 14477506HCID 14477506, compound

Product 1

HCID 14477508HCID 14477508, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 6228DimethylformamideSolvent

Procedure

To a reaction vessel having 200 ml of capacity, and fitted with stirring means, 100 ml of DMF, 5.0 g (9.35 mmol) of Boc-Asn-Asn-Pro-OBzl and 2 g of Pd catalyst (10% of Pd on coal) are charged.

Workup

  1. customTo a reaction vessel having
  2. additionare charged

Sources & evidence

ORD record
ord-3c627df0c7244e688fcc0cb74eb2af9f
Source dataset
uspto-grants-1993_06
Patent number
US05219987

Reaction notes

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