HCID 67855032, compound → HCID 19756852, compound

HRID 1588037Notes

Reaction equation

HRID 1588037 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]([NH:12][C:13]([NH:15][CH:16]([CH3:18])[CH3:17])=[O:14])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].NC1C=C(C(NC(NC(C)C)=O)=O)C=CC=1>C(O)C.[Pd]>[N+:1]([C:4]1[CH:5]=[C:6]([C:10]([NH:12][C:13]([NH:15][CH:16]([CH3:18])[CH3:17])=[O:14])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 1

HCID 67855032HCID 67855032, compound

Product 1

HCID 19756852HCID 19756852, compoundYield 137.9%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3-Amino-N-(2-propylaminocarbonyl)phenylcarboxamide 3-Nitro-N-(2-propylaminocarbonyl)phenylcarboxamide (1.5 g) was dissolved in 150 ml of ethanol, treated with 850 mg of 10% palladium/carbon catalyst, and hydrogenated on a Parr apparatus at 30 psi for 10 minutes. The reaction mixture was filtered through Celite and concentrated to give the title compound (1.1 g) as a solid.

Workup

  1. filtrationThe reaction mixture was filtered through Celite
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-76165d9f4c394bee987027deb27da369
Source dataset
uspto-grants-1993_06
Patent number
US05220018

Reaction notes

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