2-Methyl-5-(3-nitrophenyl)-2H-tetrazole → HCID 178507542, compound

HRID 1588041Notes

Reaction equation

HRID 1588041 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[N:11]=[N:12][N:13](C)[N:14]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([C:10]2[NH:14][N:13]=[N:12][N:11]=2)[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 140450862-Methyl-5-(3-nitrophenyl)-2H-tetrazole

Product 1

HCID 178507542HCID 178507542, compoundYield 92.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3-Nitro-(2-methyltetrazol-5-yl)benzene (648 mg) was dissolved in 100 ml of ethanol, treated with 0.283 g of 10% palladium/carbon catalyst, and hydrogenated on a Parr apparatus at 30 psi for 15 minutes. The reaction mixture was filtered through Celite and concentrated to give 0.469 g of the title compound.

Workup

  1. filtrationThe reaction mixture was filtered through Celite
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-ed347d81b1bc43448fd747b6b78be16f
Source dataset
uspto-grants-1993_06
Patent number
US05220018

Reaction notes

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