huagongshe.com
HRID1588198

反应详情

EQUATION

反应方程式

HRID 1588198 的结构方程式

REACTANTS

反应物

3
结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：O=C1CSC(=S)N1c1ccc(O)cc1
HCID210591

Rhodanine, 3-(p-hydroxyphenyl)-

C9H7NO2S2

结构：COc1cc(C=O)ccc1O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
HCID11515167

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C=C2SC(=S)N(c3ccc(O)cc3)C2=O)ccc1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
HCID53882719

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

3-(4-Hydroxyphenyl)-2-thioxothiazolidin-4-one (0.23 g, 1.0 mmol) was added to a suspension of 4-formyl-2-methoxyphenyl β-D-galactopyranoside (1c)(0.32 g, 1.0 mmol) in methanol (20 ml) containing a drop of piperidine. The mixture, which rapidly turned yellow, was gently heated under reflux and deposited a thick precipitate after 30 min. The mixture was then cooled and filtered to give the required product (5c){0.12 g, 23%, m.p. decomp.>230° C., [α]D -34.4° (c 0.6, DMOS)}(Found: C, 53.04; H, 4.55; N, 2.81. C23H23NO9S2 requires C, 52.96; H, 4.44; N, 2.68%).

WORKUP

后处理

  1. temperatureThe mixture, which rapidly turned yellow, was gently heated
  2. temperatureunder reflux
  3. customafter 30 min
  4. temperatureThe mixture was then cooled
  5. filtrationfiltered