Oxalyl chloride → 4,4,4-Trifluorobutanoyl chloride

HRID 1588358Notes

Reaction equation

HRID 1588358 reaction equation
[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5](O)=[O:6].C(Cl)(=O)C([Cl:13])=O>C1C=CC=CC=1>[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5]([Cl:13])=[O:6]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 27770854,4,4-Trifluorobutanoic acid

Product 1

HCID 151044744,4,4-Trifluorobutanoyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4,4,4-Trifluorobutyric acid (5.8 g, 0.041 mole) was dissolved in benzene (30 ml). Oxalyl chloride (6.2 g, 0.049 mole) was added and the reaction stirred for 20 hrs. The benzene and excess oxalyl chloride was removed by distillation to give the title compound.

Workup

  1. customThe benzene and excess oxalyl chloride was removed by distillation

Sources & evidence

ORD record
ord-28ba1a7bcf4340c29c15a9ec2f739554
Source dataset
uspto-grants-1993_06
Patent number
US05221746

Reaction notes

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