反应详情

In 2.5 liters of ethanol was dissolved 1.0 kg of ethyl pivaloylacetate and 320 g of hydrazine hydrate was added dropwise to the solution under water-cooling. Thereafter, the reaction was performed overnight at room temperature and then 5.0 liters of water was added to the reaction mixture followed by stirring. Crystals thus deposited were recovered by filtration under reduced pressure, washed well with water, then washed with a small amount of methanol, and air-dried. Thus, 812 g of the above-described compound was obtained with a yield of 98.5%.

1. additionwas added dropwise to the solution under water-
2. temperaturecooling
3. filtrationCrystals thus deposited were recovered by filtration under reduced pressure
4. washwashed well with water
5. washwashed with a small amount of methanol
6. customair-dried