反应详情

After mixing 200 g of ethyl 4-chloro-3-nitrobenzoate, 500 ml of dimethyl sulfoxide, 169 g of 5-phenylisoxazole, and 146 g of potassium carbonate, the reaction was performed for 5 hours at 60° C. After the reaction was over, the reaction mixture was cooled and poured into water to deposit crystals which were then recovered, washed with water, and dried to provide 292 g of the desired product with a yield of 94.6%. The melting point thereof was 142° C. to 143° C.

1. temperaturewas cooled
2. customwere then recovered
3. washwashed with water
4. customdried