反应详情

After mixing 32 g of 4-methanesulfonyl-2-tetradecylsulfonylchlorobenzene, 20 g of 5-t-butyl-3-hydroxyisoxazole, 20 g of potassium carbonate, and 140 ml of dimethyl sulfoxide, the reaction was performed for 4 hours at 80° C. After the reaction was over, the reaction mixture formed was poured into water and extracted with ethyl acetate. The organic phase obtained was purified by silica gel column chromatography and 20.0 g of the desired compound was obtained as the main product with a yield of 50.8%. The melting point thereof was 85° C. to 86° C.

1. customformed
2. extractionextracted with ethyl acetate
3. customThe organic phase obtained
4. customwas purified by silica gel column chromatography