2,2-Diphenylacetyl chloride → HCID 19754058, compound

HRID 1588578Notes

Reaction equation

HRID 1588578 reaction equation
[CH2:1]([C:5]1[N:21]([CH2:22][C:23]2[CH:28]=[CH:27][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[S:35]([NH2:38])(=[O:37])=[O:36])=[CH:25][CH:24]=2)[C:8]2=[N:9][CH:10]=[C:11]([NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18][CH3:19])[C:12]([CH3:13])=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4].[C:39]1([CH:45]([C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)[C:46](Cl)=[O:47])[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[CH2:1]([C:5]1[N:21]([CH2:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[S:35]([NH:38][C:46](=[O:47])[CH:45]([C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)[C:49]3[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=3)(=[O:37])=[O:36])=[CH:27][CH:28]=2)[C:8]2=[N:9][CH:10]=[C:11]([NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18][CH3:19])[C:12]([CH3:13])=[C:7]2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 19754052HCID 19754052, compound

Product 1

HCID 19754058HCID 19754058, compound

Procedure

The title compound was prepared from 2-butyl-3-[[2'-[(amino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-7-methyl-6-[(1-oxopentyl)amino]-3H-imidazo[4,5-b]pyridine and diphenylacetyl chloride as described in Example 1, Step 5.

Sources & evidence

ORD record
ord-a0d0f7631df745219b329385767905b7
Source dataset
uspto-grants-1993_06
Patent number
US05223499

Reaction notes

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