Acetic Anhydride → HCID 178476378, compound

HRID 1588646Notes

Reaction equation

HRID 1588646 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][NH:6][C:5]1=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1.[C:22](OC(=O)C)(=[O:24])[CH3:23]>ClCCl>[C:22]([O:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][NH:6][C:5]1=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1)(=[O:24])[CH3:23]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 178521200HCID 178521200, compound

Product 1

HCID 178476378HCID 178476378, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Reaction of 4-(2-[1-(2-hydroxyethyl)-2-imidazolidinylideneamino]phenyl)morpholine (3 g prepared as described in Example 175) in dichloromethane (20 ml) with acetic anhydride (0.86 g) yielded 4-(2-[1-(2-acetyloxyethyl)-2-imidazolidinylideneamino]phenyl)morpholine (m.p. 89°-91° C.) which was recrystallised from hexane.

Sources & evidence

ORD record
ord-65b83e9cc8624136a9f57ceb80690172
Source dataset
uspto-grants-1993_06
Patent number
US05223498

Reaction notes

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