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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1588973Generated: November 2, 2026

4-(3-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide → 4-(3-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine

https://huagongshe.com/reaction/1588973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998754—
ReactantAluminium lithium hydrideHCID 21226445—
Product4-(3-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamineHCID 14998771—

Reaction Steps

In a manner similar to Preparation 2, react 4-(3-methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide (0.9 g, 27 mmol) with lithium aluminum hydride (2.1 g, 55 mmol) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05223623
Source datasetuspto-grants-1993_06
ORD IDord-a50557f6ef2c4d69b36e8b4588fcc57e
Source noteuspto-grants-1993_06