HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[4-[[[1-phenyl-4-(phenylmethyl)piperazin-2-yl]methyl]amino]phenyl]methanesulfonamide, hydrochloride → N-[4-[[(1-Phenylpiperazin-2-yl)methyl]amino]phenyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[4-[[[1-phenyl-4-(phenylmethyl)piperazin-2-yl]methyl]amino]phenyl]methanesulfonamide, hydrochloride | HCID 131718014 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | N-[4-[[(1-Phenylpiperazin-2-yl)methyl]amino]phenyl]methanesulfonamide | HCID 14998853 | — |
| Product | CH3CN NH4OH | HCID 19098099 | — |
Reaction Steps
In a manner similar to Example 1, react N-[4-[[[1-phenyl-4-(phenylmethyl)piperazin-2-yl]methyl]amino]phenyl]methanesulfonamide, hydrochloride (2.92 g, 6.0 mmol) with H2 over 10% palladium on activated charcoal (0.29 g). Chromatograph the residue on silica with CH2CN/NH4OH (99/1) to obtain the title compound,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05223623 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-9436e68ff226412eb465144e8c7d7cc7 |
| Source note | uspto-grants-1993_06 |