Acrylonitrile → 1H-1,2,4-Triazole-1-propanamine

HRID 1589162Notes

Reaction equation

HRID 1589162 reaction equation
[C:1](#[N:4])[CH:2]=[CH2:3].[NH:5]1[CH:9]=[N:8][CH:7]=[N:6]1>>[N:5]1([CH2:3][CH2:2][CH2:1][NH2:4])[CH:9]=[N:8][CH:7]=[N:6]1

Participants

3

Reactant 2

HCID 7855AcrylonitrileHCID 92571H-1,2,4-Triazole

Product 1

HCID 43796821H-1,2,4-Triazole-1-propanamine

Procedure

Acrylonitrile (5) and 1H-1,2,4-triazole (2) are reacted with heat for about 2-4 hours, concentrated to an oil and then hydrogenated with Raney nickel catalyst in methanol and ammonium hydroxide for a period of about 8-10 hours, giving 1H-1,2,4-triazole-1-propanamine (6).

Workup

  1. temperaturewith heat for about 2-4 hours
  2. concentrationconcentrated to an oil

Sources & evidence

ORD record
ord-107dc67aea474d7a9d532df98da20a0b
Source dataset
uspto-grants-1986_02
Patent number
US04568685

Reaction notes

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