Isatoic Anhydride → HCID 13588895, compound

HRID 1589170Notes

Reaction equation

HRID 1589170 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][NH2:9])[CH:5]=[N:4][CH:3]=[N:2]1.[C:10]12[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=1)[NH:15]C(=O)O[C:11]2=[O:12]>C(O)C>[NH2:15][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:10]=1[C:11]([NH:9][CH2:8][CH2:7][CH2:6][N:1]1[CH:5]=[N:4][CH:3]=[N:2]1)=[O:12]

Participants

4

Reactant 2

HCID 8359Isatoic AnhydrideHCID 43796821H-1,2,4-Triazole-1-propanamine

Product 1

HCID 13588895HCID 13588895, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
70 °C

Procedure

A mixture of about 2.5 g of 1H-1,2,4-triazole-1-propanamine, about 3.26 g of isatoic anhydride and about 20 ml of ethanol was heated in an oil bath at about 70° C. for about 30 minutes and then concentrated. The residue was recrystallized from ethyl acetate and the desired product, mp 96°-98° C., was obtained.

Workup

  1. concentrationconcentrated
  2. customThe residue was recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-349cbd8ccec849698bcb934bd5f2207d
Source dataset
uspto-grants-1986_02
Patent number
US04568685

Reaction notes

Loading…