Phthalimide → N-[4-(imidazol-1-yl)butyl]phthalimide

HRID 1589194Notes

Reaction equation

HRID 1589194 reaction equation
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[N:12]1([CH2:17][CH2:18][CH2:19][CH2:20]N)[CH:16]=[CH:15][N:14]=[CH:13]1>>[N:12]1([CH2:17][CH2:18][CH2:19][CH2:20][N:5]2[C:1](=[O:11])[C:2]3[C:3](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:4]2=[O:6])[CH:16]=[CH:15][N:14]=[CH:13]1

Participants

3

Reactant 2

HCID 6809PhthalimideHCID 43794804-(1H-imidazol-1-yl)butan-1-amine

Product 1

HCID 13290795N-[4-(imidazol-1-yl)butyl]phthalimide

Procedure

A mixture of 0.01 mole of phthalimide and 0.01 mole of 1H-imidazol-1-butanamine was heated in an oil bath at 140° for 1 hour. The reaction mixture was cooled to obtain the desired product.

Workup

  1. temperaturewas heated in an oil bath at 140° for 1 hour
  2. temperatureThe reaction mixture was cooled

Sources & evidence

ORD record
ord-6da97bbb27974d90b81bb68b4e5439e9
Source dataset
uspto-grants-1986_02
Patent number
US04568687

Reaction notes

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