反应详情

30 g (1 mole) of paraformaldehyde, 107 ml of 1-octanol (1 mole) are stirred in 100 ml chloroform at 0°-5° C., by passing HBr gas. After the reaction completion, indicated by the complete dissolution of the solid, the organic layer is washed with water several times, and dried over anhydrous sodium sulphate. The residue is diluted in chloroform, to give a 3M solution. The product boiled at 150°-155° C. (1 torr) and has a singlet (2 hydrogens) at 5.8 ppm from TMS. The product is kept refrigerated.

1. dissolutionAfter the reaction completion, indicated by the complete dissolution of the solid
2. washthe organic layer is washed with water several times
3. dry with materialdried over anhydrous sodium sulphate
4. additionThe residue is diluted in chloroform