Hydrogen Peroxide → m-(2-Hydroperoxy-2-propyl)acetophenone

HRID 1589286Notes

Reaction equation

HRID 1589286 reaction equation
[OH:1][C:2]([C:5]1[CH:6]=[C:7]([C:11](=[O:13])[CH3:12])[CH:8]=[CH:9][CH:10]=1)([CH3:4])[CH3:3].OO.C(C1C=CC=CC=1)(=[O:18])C>>[O:1]([C:2]([C:5]1[CH:6]=[C:7]([C:11](=[O:13])[CH3:12])[CH:8]=[CH:9][CH:10]=1)([CH3:4])[CH3:3])[OH:18]

Participants

4

Reactant 3

HCID 784Hydrogen PeroxideHCID 7410AcetophenoneHCID 135314191-(3-(1-Hydroxy-1-methylethyl)phenyl)ethanone

Product 1

HCID 13531420m-(2-Hydroperoxy-2-propyl)acetophenone

Procedure

A process for producing m-hydroxyacetophenone which comprises reacting m-(2-hydroxy-2-propyl)acetophenone with 1 to 20 moles of 5 to 90% by weight aqueous hydrogen peroxide solution per mole of said acetophenone at 30° to 95° C. in the presence of a mineral acid catalyst to form m-(2-hydroperoxy-2-propyl)acetophenone, and then decomposing the m-(2-hydroperoxy-2-propyl)acetophenone by warming with sulfuric acid, hydrochloric acid, perchloric acid, boron trifluoride, sulfuric acid anhydride or toluenesulfonic acid to form m-hydroxyacetophenone.

Workup

  1. customA process for producing m-hydroxyacetophenone which
  2. customat 30° to 95° C.

Sources & evidence

ORD record
ord-4c98434be55d4daab29ae03a20617e05
Source dataset
uspto-grants-1986_02
Patent number
US04568768

Reaction notes

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