HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-4-(methylthio)benzoyl chloride → 4-(2-Methoxy-4-methylmercapto-benzoylamino)-5-nitro-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-4-(methylthio)benzoyl chloride | HCID 2759591 | — |
| Reactant | 4-Amino-5-nitro-2-pyridinol | HCID 13520933 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 4-(2-Methoxy-4-methylmercapto-benzoylamino)-5-nitro-1H-pyridin-2-one | HCID 13520934 | — |
Reaction Steps
A mixture of 0.45 g of 4-amino-5-nitro-1H-pyridin-2-one and 0.87 g of 2-methoxy-4-methylmercapto-benzoyl chloride was refluxed for 8 hours in 10 ml of chlorobenzene. The precipitated product was suction-filtered off, washed with methylene chloride and used in the next step as the crude product without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04568680 |
| Source dataset | uspto-grants-1986_02 |
| ORD ID | ord-945ebead078c45ba8c3174554b87020d |
| Source note | uspto-grants-1986_02 |