Sodium → HCID 13577513, compound

HRID 1589330Notes

Reaction equation

HRID 1589330 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([S:11][CH2:12][CH2:13]Cl)=[N:9][OH:10])=[CH:4][CH:3]=1.[Na]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:11][CH2:12][CH2:13][O:10][N:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 5360545SodiumHCID 86740659HCID 86740659, compound

Product 1

HCID 13577513HCID 13577513, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Chloroethyl 4-chloro-N-hydroxybenzenecarboximidothioate (2.5 g, 0.01 mol) was cyclised with sodium (0.23 g) in ethanol (25 ml) as described in Example 2. 3-(4-Chlorophenyl)-5,6-dihydro-1,4,2-oxathiazine, mp 80.5°-81.5° C., was isolated. (Found: C,50.16; H,4.24; N,6.44. C9H8ClNOS requires C,50.58; H,3.77; N,6.55.)

Sources & evidence

ORD record
ord-8a166f43d9df4520b8a83a09819790ab
Source dataset
uspto-grants-1986_02
Patent number
US04569690

Reaction notes

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