HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-Methoxy-5-(pyrrolidine-1-sulfonyl)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 5-Chlorosulphonyl-2-anisic acid | HCID 104007 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Methoxy-5-(pyrrolidine-1-sulfonyl)-benzoic acid | HCID 737348 | — |
Reaction Steps
5-Chlorosulphonyl-2-methoxybenzoic acid (4.9 g) was added to a solution of pyrrolidine (10 g) in water (150 ml). The solution was stirred for 6 hours, filtered and acidified with dilute hydrochloric acid to yield the title compound as colourless microcrystals (5.27 g; 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04569940 |
| Source dataset | uspto-grants-1986_02 |
| ORD ID | ord-0000e4af13c64b479b730aa29731b5e7 |
| Source note | uspto-grants-1986_02 |