Hydrochloric Acid → HCID 136387256, compound

HRID 1589482Notes

Reaction equation

HRID 1589482 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([O:10][CH3:11])[CH:4]=1)#[N:2].[ClH:12].[CH3:13][OH:14]>>[ClH:12].[CH3:13][O:14][N:2]=[CH:1][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([O:10][CH3:11])[CH:4]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 781354-Hydroxy-3-methoxybenzonitrile

Product 1

HCID 136387256HCID 136387256, compound

Procedure

In 50 ml of anhydrous methanol, was dissolved 7.5 g of 4-cyano-2-methoxyphenol. The solution was saturated with dried gaseous hydrogen chloride, while being cooled in ice and stirred, and then stirred overnight at room temperature to precipitate yellow crystals. After addition of ethyl ether, the crystals were collected by filtration, washed with ethyl ether and dried to obtain 9.4 g of 4-methoxyiminomethyl-2-methoxyphenol hydrochloride.

Workup

  1. temperaturewhile being cooled in ice
  2. stirringstirred overnight at room temperature
  3. customto precipitate yellow crystals
  4. additionAfter addition of ethyl ether
  5. filtrationthe crystals were collected by filtration
  6. washwashed with ethyl ether
  7. customdried

Sources & evidence

ORD record
ord-2af6db5fbc0f48e3ae0c288b88142b39
Source dataset
uspto-grants-1986_02
Patent number
US04570006

Reaction notes

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