反应详情

Similarly prepared by this procedure from 1-amino-3-[3-(dimethylaminomethyl)phenoxy]-2-propanol (1.5 g) and compound B (2.25 g) except that the methyl isobutyl ketone extract was evaporated to give a solid which was washed with diethyl ether and then recrystallised from methyl acetate was 5-[[3-[3-(dimethylaminomethyl)phenoxy]-2-hydroxy-propyl]amino]-1-methyl-1H-1,2,4-triazole-3-methanol (250 mg) m.p. 104°-109°.

1. extractionextract
2. customwas evaporated
3. customto give a solid which
4. washwas washed with diethyl ether
5. customrecrystallised from methyl acetate