Sodium Hydroxide → HCID 13559251, compound

HRID 1589676Notes

Reaction equation

HRID 1589676 reaction equation
C([O:4][C:5]1[CH:29]=[CH:28][C:8]([C:9]([O:11][C:12]2[CH:27]=[CH:26][C:15]([C:16]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:17])=[CH:14][CH:13]=2)=[O:10])=[CH:7][CH:6]=1)(=O)C.[OH-].[Na+]>O1CCCC1>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([C:9]([O:11][C:12]2[CH:27]=[CH:26][C:15]([C:16]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:17])=[CH:14][CH:13]=2)=[O:10])=[CH:28][CH:29]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 135877394-[(Benzyloxy)carbonyl]phenyl 4-(acetyloxy)benzoate

Product 1

HCID 13559251HCID 13559251, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Subsequently, a 100 ml four-necked flask equipped with a condenser tube and a thermometer was charged with 15.6 g of benzyl p-(p-acetoxybenzoyloxy)benzoate, 30 g of 5% sodium hydroxide and 50 ml of tetrahydrofuran, and they were reacted at 30° C. for 5 hours. The reaction product was extracted with 50 ml of toluene. The extract was washed with water, and toluene was evaporated. The residue was separated on a column to give benzyl p-(p-hydroxybenzoyloxy)benzoate as white crystals having a melting point of 137° to 138.5° C.

Workup

  1. customSubsequently, a 100 ml four-necked flask equipped with a condenser tube
  2. customwere reacted at 30° C. for 5 hours
  3. extractionThe reaction product was extracted with 50 ml of toluene
  4. washThe extract was washed with water, and toluene
  5. customwas evaporated
  6. customThe residue was separated on a column

Sources & evidence

ORD record
ord-4c715d2f85e24b64b9ddc4c85daf16b5
Source dataset
uspto-grants-1986_02
Patent number
US04573062

Reaction notes

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