Hydrochloric Acid → HCID 178479547, compound

HRID 1589737Notes

Reaction equation

HRID 1589737 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[F:10])[C:5]#[N:6].[ClH:11].C([OH:14])C>>[ClH:11].[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[F:10])[C:5](=[NH:6])[OH:14]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 5872033,4-Difluorobenzonitrile

Product 1

HCID 178479547HCID 178479547, compound

Procedure

In anhydrous ethanol, compound [L'], commercially available 3,4-difluorobenzonitrile is reacted with gaseous hydrogen chloride to yield compound [M'], 3,4-difluorobenzimidate hydrogen chloride. In ethanol, compound [M'] is reacted with gaseous ammonia to yield compound [N'], 3,4-difluorobenzamidine hydrogen chloride.

Sources & evidence

ORD record
ord-0c5043902fa84822a3e9c1c292cbfad0
Source dataset
uspto-grants-1993_04
Patent number
US05200110

Reaction notes

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