HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 4-Bromo-3,5-difluorobenzimidamide Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 178479548 | HCID 178479548 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Bromo-3,5-difluorobenzimidamide Hydrochloride | HCID 19838583 | — |
Reaction Steps
450 cm3 of anhydrous ethanol saturated with dried gaseous ammonia was added to 4-bromo-3,5-difluorobenzimidate hydrogen chloride and stirred overnight at room temperature. About one-half of the volume of the solvent was distilled off and the residue was recrystallized to yield 90 g (0.36 mol) of 4-bromo-3,5-difluorobenzamidine hydrogen chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05200110 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-f6eec6f26b3e4653a55336994f5e4806 |
| Source note | uspto-grants-1993_04 |