Sodium Hydroxide → HCID 19770972, compound

HRID 1589843Notes

Reaction equation

HRID 1589843 reaction equation
[CH2:1]([C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12]([O:14]CC)=[O:13])=[C:7]2[CH:6]=[CH:5][CH:4]=1)[CH3:2].[OH-].[Na+]>C(O)C>[CH2:1]([C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12]([OH:14])=[O:13])=[C:7]2[CH:6]=[CH:5][CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19770953HCID 19770953, compound

Product 1

HCID 19770972HCID 19770972, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
100 °C

Procedure

To 0.40 g (1.83 mmol) of ethyl 7-ethylpyrazolo[1,5-a]pyridine-3-carboxylate, 8 ml of 2.5N aq. NaOH solution and 8 ml of ethanol were added, followed by stirring at 100° C. for 8 hours. After the reaction, post treatments were conducted in a similar manner to the syntheses bf the 5-methyl and 2,7-dimethyl derivatives so that crystals were obtained. Yield: 0.34 g (1.79 mmol) (98%).

Workup

  1. customAfter the reaction, post treatments
  2. customwere obtained

Sources & evidence

ORD record
ord-411e970b60a749c9aa5326c383e916da
Source dataset
uspto-grants-1993_04
Patent number
US05200415

Reaction notes

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