Benzoyl chloride → HCID 15676487, compound

HRID 1589852Notes

Reaction equation

HRID 1589852 reaction equation
[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].C(=O)([O-])[O-].[K+].[K+].[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:16](=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 11430Potassium CarbonateHCID 114124382-Chloro-m-toluidine

Product 1

HCID 15676487HCID 15676487, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

57 g (0.4 mol) of 2-chloro-3-methyl-aniline [CA 89, 30772h) were dissolved in 1.5 1 of toluene, 55 g of potassium carbonate were added and 62 g (0.4 mol) of benzoyl chloride were added dropwise at 80° C. After reaction is complete, the solid was filtered off in the cold and washed with water, and the filtrate was dried. After concentrating and triturating with petroleum ether 98 g of product (100%) crystallized.

Workup

  1. additionwere added
  2. customAfter reaction
  3. filtrationthe solid was filtered off in the cold
  4. washwashed with water
  5. customthe filtrate was dried
  6. concentrationAfter concentrating
  7. customtriturating with petroleum ether 98 g of product (100%)
  8. customcrystallized

Sources & evidence

ORD record
ord-8a4cf2acdd814a3888df083d166e96a4
Source dataset
uspto-grants-1993_04
Patent number
US05200420

Reaction notes

Loading…