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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1590110Generated: October 30, 2026

Glycidyl tosylate → 3-(Pyrazolo[1,5-a]pyrid-4-yloxy)-1,2-epoxypropane

https://huagongshe.com/reaction/1590110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycidyl tosylateHCID 160868—
ReactantPyrazolo(1,5-a)pyridin-4-olHCID 15257896—
Product3-(Pyrazolo[1,5-a]pyrid-4-yloxy)-1,2-epoxypropaneHCID 15257898—

Reaction Steps

4-Hydroxypyrazolo[1,5-a]pyridine (5) as obtained by the above procedure is reacted, in the form of alkali metal salt, with glycidyl tosylate to give 3-(pyrazolo[1,5-a]pyrid-4-yloxy)-1,2-epoxypropane (6). The reaction is preferably carried out in a solvent such as dimethylformamide under an atmosphere of argon gas.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05202334
Source datasetuspto-grants-1993_04
ORD IDord-14df4bc3f46642bdae096f97f4d4fa6e
Source noteuspto-grants-1993_04