Octahydro-6-methyl-1-(phenylmethyl)pyrrolo[3,4-b]pyrrole → HCID 22924398, compound

Participants

Reaction Steps

7.8 g (36 mmol) of 2-benzyl-8-methyl-2,7-diazabicyclo[3.3.0]octane in 200 ml of ethanol are hydrogenated on 2 g of palladium/active carbon (10% Pd) at 100° C. and 100 bar. The catalyst is filtered off with suction, the filtrate is concentrated, and the residue is distilled. The distillate crystallises.

Provenance & Evidence