Hydroxyamine hydrochloride → 3-(Phenylethynyl)-benzaldehyde oxime

HRID 1590220Notes

Reaction equation

HRID 1590220 reaction equation
[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[CH:12]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:18][OH:19].C([O-])(=O)C.[Na+]>>[C:1]1([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[CH:12]=[N:18][OH:19])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium AcetateHCID 31450113-Phenylethynyl-benzaldehyde

Product 1

HCID 727471633-(Phenylethynyl)-benzaldehyde oxime

Procedure

The procedure was the same as described in Example 1b, except there were used 16.5 g of 3-(phenylethynyl)-benzaldehyde, 8.3 g of hydroxylamine hydrochloride and 8.2 g of sodium acetate to give 16.8 g (94.8% of the theoretical yield) of the title compound in form of a yellowish powder (mixture of isomers).

Workup

  1. customto give 16.8 g (94.8% of the

Sources & evidence

ORD record
ord-c3ff691b014f4d7997f301c01b8af1ff
Source dataset
uspto-grants-1993_04
Patent number
US05202349

Reaction notes

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