HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → Ethyl 4-(hydroxyimino)-5-oxo-1-phenyl-3-pyrrolidineacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Ethyl 4,5-dioxo-1-phenyl-3-pyrrolidineacetate | HCID 57059855 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Ethyl 4-(hydroxyimino)-5-oxo-1-phenyl-3-pyrrolidineacetate | HCID 86746704 | — |
Reaction Steps
A solution of product of Example 62 in pyridine is treated with an excess of hydroxylamine hydrochloride and the reaction is stirred at room temperature for 2 d. The solution is concentrated in vacuo and the residue is chromatographed on silica gel to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05202344 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-94d20b50deb44793a86bc515156acfef |
| Source note | uspto-grants-1993_04 |