Ethanol → E-1-(3,4-dichlorophenyl)-3,3-diethoxy but-1-ene

HRID 1590389노트

반응식

HRID 1590389 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10]C=O)[CH:5]=[CH:6][C:7]=1[Cl:8].[CH:13]([O:20][CH2:21][CH3:22])([O:17][CH2:18][CH3:19])OCC.[N+]([O-])([O-])=O.[NH4+].[CH2:28](O)C>>[Cl:1][C:2]1[CH:3]=[C:4](/[CH:9]=[CH:10]/[C:13]([O:17][CH2:18][CH3:19])([O:20][CH2:21][CH3:22])[CH3:28])[CH:5]=[CH:6][C:7]=1[Cl:8]

참가 물질

5

반응물 4

HCID 702EthanolHCID 22985Ammonium nitrateHCID 31214Ethyl orthoformateHCID 538805763,4-Dichlorocinnamaldehyde

생성물 1

HCID 19769940E-1-(3,4-dichlorophenyl)-3,3-diethoxy but-1-ene

실험 절차

The above aldehyde (0.66 g) was stirred in ethanol (5 ml) with triethyl orthoformate (0.6 ml) (ex Aldrich) and ammonium nitrate (ex Aldrich) (0.01 g) for 3.5 hours at 25°. Concentration in vacuo and work up in the usual manner gave E-1-(3,4-dichlorophenyl)-3,3-diethoxy but-1-ene (0.97g). NMR 1H: 7.32(3H,m), 6.79(1H,d), 6.19(1H,dd), 5.08(1H,d), 3.69(4H,m), 1.29(6H,m).

후처리

  1. concentrationConcentration in vacuo

출처 및 근거

ORD 기록
ord-a682a9ea719441b1a4ae4a5fecb43924
출처 데이터셋
uspto-grants-1993_04
특허 번호
US05202356

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