Ethyl Acrylate → HCID 53920211, compound
Reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH:2]=[CH2:3].[Cl:8][C:9]1[CH:21]=[CH:20][C:12]2[O:13][CH:14]([CH2:17][NH:18][CH3:19])[CH2:15][O:16][C:11]=2[CH:10]=1>>[CH2:6]([O:5][C:1](=[O:4])[CH2:2][CH2:3][N:18]([CH2:17][CH:14]1[O:13][C:12]2[CH:20]=[CH:21][C:9]([Cl:8])=[CH:10][C:11]=2[O:16][CH2:15]1)[CH3:19])[CH3:7]Participants
3
Procedure
3.3 ml (0.03 mol) of ethyl acrylate are added to 5.0 g (0.023 mol) of 6-chloro-2-methylaminomethylbenzo-1,4-dioxane and the reaction mixture is allowed to stand for 60 hours at room temperature, yielding crude 3-[N-(6-chlorobenzo-1,4-dioxan-2-ylmethyl)-N-methylamino]-propionic acid ethyl ester which can be used without further purification.
Sources & evidence
- ORD record
- ord-fb28b49eb9b544d3bd62d67e2ef46136
- Source dataset
- uspto-grants-1993_04
- Patent number
- US05204334
Reaction notes
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