Cyclohexylamine → HCID 19768194, compound

HRID 1590765Notes

Reaction equation

HRID 1590765 reaction equation
[CH:1]1([NH2:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].[SH:10][C:11]1[S:12][CH2:13][CH2:14][N:15]=1.Cl[O-].[Na+]>O>[CH:1]1([NH:7][S:10][C:11]2[S:12][CH2:13][CH2:14][N:15]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

6

Reactant 4

HCID 7965CyclohexylamineHCID 14798Sodium HydroxideHCID 23665760Sodium HypochloriteHCID 178527880HCID 178527880, compound

Product 1

HCID 19768194HCID 19768194, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 12.3 g (124 mmole) of cyclohexylamine and 30 ml of water was thoroughly stirred in an ice bath, and 30 ml of a 1N sodium hydroxide aqueous solution having dissolved therein 3.57 g (30 mmole) of 2-mercaptothiazoline and 22.3 ml (30 mmole) of a 10% sodium hypochlorite aqueous solution were simultaneously added thereto dropwise. After allowing the mixture to react at room temperature for 1 hour, the reaction mixture was filtered with suction. The resulting solid was washed with water and dried under reduced pressure to obtain 5.61 g (26 mmole) of the titled compound in a percent yield of 87%.

Workup

  1. customto react at room temperature for 1 hour
  2. filtrationthe reaction mixture was filtered with suction
  3. washThe resulting solid was washed with water
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-fa358a0e2b174f309e28a5e845eab4ee
Source dataset
uspto-grants-1993_04
Patent number
US05204461

Reaction notes

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