Cyclohexylamine → HCID 19768194, compound

Participants

Reaction Steps

A mixture of 12.3 g (124 mmole) of cyclohexylamine and 30 ml of water was thoroughly stirred in an ice bath, and 30 ml of a 1N sodium hydroxide aqueous solution having dissolved therein 3.57 g (30 mmole) of 2-mercaptothiazoline and 22.3 ml (30 mmole) of a 10% sodium hypochlorite aqueous solution were simultaneously added thereto dropwise. After allowing the mixture to react at room temperature for 1 hour, the reaction mixture was filtered with suction. The resulting solid was washed with water and dried under reduced pressure to obtain 5.61 g (26 mmole) of the titled compound in a percent yield of 87%.

Provenance & Evidence