Triphenylphosphine → 4-(2'-amino-1'-methyl-5'-oxo-2-phenyl-1',5'-dihydrospiro[chroman-4,4'-imidazole]-6-yl)-N-(2-(dimethylamino)ethyl)benzamide
Reaction equation
[C:48](=[O:49])([O-:50])[O-:51].[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[CH3:25][N:26]([CH2:27][CH2:28][NH:29][C:30](=[O:31])[c:32]1[cH:33][cH:34][c:35]([B:38]([OH:39])[OH:40])[cH:36][cH:37]1)[CH3:41].[Cs+:52].[Cs+:53].[NH2:1][C:2]1=[N:22][C:5]2([C:4](=[O:23])[N:3]1[CH3:24])[CH2:6][CH:7]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[O:8][c:9]1[cH:10][cH:11][c:12]([Br:15])[cH:13][c:14]12.[Pd:54]([Cl:55])[Cl:56].[c:57]1([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[cH:71][cH:72][cH:73][cH:74][cH:75]1.[c:76]1([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[cH:90][cH:91][cH:92][cH:93][cH:94]1>>[NH2:1][C:2]1=[N:22][C:5]2([C:4](=[O:23])[N:3]1[CH3:24])[CH2:6][CH:7]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[O:8][c:9]1[cH:10][cH:11][c:12](-[c:35]3[cH:34][cH:33][c:32]([C:30]([NH:29][CH2:28][CH2:27][N:26]([CH3:25])[CH3:41])=[O:31])[cH:37][cH:36]3)[cH:13][c:14]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b9dc80fb646a4b798fe08020aa182243
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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