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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1590973Generated: October 29, 2026

Hydrochloric Acid → BOC-Thr(Bzl)-Pro-OBzl

https://huagongshe.com/reaction/1590973

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBenzyl L-prolinateHCID 736155—
ReactantL-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-HCID 1549483—
ProductBOC-Thr(Bzl)-Pro-OBzlHCID 1500399695.3%

Reaction Steps

By using 8.66 g of Boc-Thr(Bzl)-OH and 7.42 g of HCl.H-Pro-OBzl, and the same procedure as in Reference Example 15 was repeated to obtain 13.25 g (yield: 95.3%) of the above mentioned objective product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05204326
Source datasetuspto-grants-1993_04
ORD IDord-49144918cd224e7c8117353766aa5402
Source noteuspto-grants-1993_04