HRID1590990

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID78288

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-

C7H13NO4

结构：CCOC(=O)[C@H](CC(C)C)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@H](C)NC(=O)OC(C)(C)C

HCID131717876

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)[C@H](CC(C)C)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)OC(C)(C)C

HCID131717877

未命名化合物

收率 77.8%

PROCEDURE

实验过程

By using 3.50 g of Boc-Ala-Ser(Bzl)-Leu-OEt and 1.30 g of Boc-Gly-OH, and the same procedure as in Reference Example 15 was repeated to obtain 3.03 g (yield: 77.8%) of the above-mentioned objective product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-401ba622147140c0bb8d96baf0a41c8b
来源数据集: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05204326
来源说明: uspto-grants-1993_04

反应 SMILES

[NH:1](C(OC(C)(C)C)=O)[C@H:2]([C:4]([NH:6][C@H:7]([C:17]([NH:19][C@H:20]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:21][CH:22]([CH3:24])[CH3:23])=[O:18])[CH2:8][O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:5])[CH3:3].[NH:37]([C:42]([O:44][C:45]([CH3:48])([CH3:47])[CH3:46])=[O:43])[CH2:38][C:39]([OH:41])=O>>[NH:37]([C:42]([O:44][C:45]([CH3:48])([CH3:47])[CH3:46])=[O:43])[CH2:38][C:39]([NH:1][C@H:2]([C:4]([NH:6][C@H:7]([C:17]([NH:19][C@H:20]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:21][CH:22]([CH3:24])[CH3:23])=[O:18])[CH2:8][O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:5])[CH3:3])=[O:41]