反应详情

To a solution of 3-chloro-2-hydroxypropyl hexadecyl ether (10 g, 0.0311 moles in 20 mls water at 90° C. under argon was added a 50% solution of sodium hydroxide (1.37 g, 0.0343 moles) in 10 mls water over 15 minutes. The reaction was heated under the same conditions for 3 additional hours. Sample was purified by distillation (yield=60%). Upon cooling a white solid formed.

1. temperatureThe reaction was heated under the same conditions for 3 additional hours
2. distillationSample was purified by distillation (yield=60%)
3. temperatureUpon cooling a white solid
4. customformed