HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → 6-Carbamoyl-1-(1-imidazolyl)-3,4-dihydronaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(1H-imidazol-1-yl)-7,8-dihydronaphthalene-2-carbonitrile | HCID 9837392 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-Carbamoyl-1-(1-imidazolyl)-3,4-dihydronaphthalene | HCID 19766492 | — |
Reaction Steps
Potassium carbonate and 30% aqueous H2O2 solution are added several times, within a period of 24 hours, to 6-cyano-1-(1-imidazolyl)-3,4-dihydronaphthalene (Example 1) in DMSO and CH2Cl2. Finally, water is added and the solid is filtered off, yielding the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05206256 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-1efc13136af34c82890a9eb275e816b3 |
| Source note | uspto-grants-1993_04 |