反应详情

温度

-30 °C

5-(2-Hydroxyethyl)benzofurazan (1.48 g, 9 mmol) was dissolved in dichloromethane (45 ml) and triethylamine (1.88 ml, 1.37 g, 13.5 mmol) was added. The mixture was cooled to -30° C. and methanesulfonyl chloride (0.84 ml, 1.24 g, 10.8 mmol) was added dropwise over 5 min. The mixture was stirred at -30° C. for 15 min. and dichloromethane (100 ml) was added. The mixture was washed with water (100 ml), dried (Na2SO4) and evaporated under reduced pressure to give the benzofurazan as a yellow solid (2.10 g, 96%).

1. washThe mixture was washed with water (100 ml)
2. dry with materialdried (Na2SO4)
3. customevaporated under reduced pressure