Hydrochloric Acid → HCID 19045469, compound

HRID 1591231Notes

Reaction equation

HRID 1591231 reaction equation
C(N[N:5]1[CH2:10][CH2:9][C:8]2([CH:15]([CH3:16])[C:14](=[O:17])[C:13]3[CH:18]=[C:19]([S:22]([CH3:25])(=[O:24])=[O:23])[CH:20]=[CH:21][C:12]=3[O:11]2)[CH2:7][CH2:6]1)(=O)C.[ClH:26]>CO>[ClH:26].[CH3:16][CH:15]1[C:8]2([CH2:7][CH2:6][NH:5][CH2:10][CH2:9]2)[O:11][C:12]2[CH:21]=[CH:20][C:19]([S:22]([CH3:25])(=[O:24])=[O:23])=[CH:18][C:13]=2[C:14]1=[O:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19045229HCID 19045229, compound

Product 1

HCID 19045469HCID 19045469, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of Step B (0.5 g) in CH3OH (15 mL) and 6N HCl (15 mL) was heated at reflux for 10 hours. The reaction was concentrated to dryness and the residue flushed with ethanol (4 times) and then toluene to yield 0.5 g of the title compound.

Workup

  1. temperatureat reflux for 10 hours
  2. concentrationThe reaction was concentrated to dryness
  3. customthe residue flushed with ethanol (4 times)

Sources & evidence

ORD record
ord-f0fa6826a20f4f5cbf09a2936d2ca570
Source dataset
uspto-grants-1993_04
Patent number
US05206240

Reaction notes

Loading…