Hydrochloric Acid → HCID 13742393, compound

HRID 1591290Notes

Reaction equation

HRID 1591290 reaction equation
CN(C)C=[N:4][C:5]1[S:6][C:7]([C:13]#[N:14])=[C:8]([Cl:12])[C:9]=1[C:10]#[N:11].Cl>C(O)C>[NH2:4][C:5]1[S:6][C:7]([C:13]#[N:14])=[C:8]([Cl:12])[C:9]=1[C:10]#[N:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54130712HCID 54130712, compound

Product 1

HCID 13742393HCID 13742393, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 5.4 parts of N,N-dimethyl-N'-(4-chloro-3,5-dicyanothien-2-yl)-formamidine, 40 parts of ethanol and 4.5 parts of concentrated hydrochloric acid is heated at the boil for 2 hours and filtered while hot, and the filtrate is poured into 100 parts of water. The precipitate which separates out is filtered off under suction, washed with water and dried. 3.8 g (92% of theory) of 2-amino-4-chloro-3,5-dicyanothiophene are obtained.

Workup

  1. temperatureis heated at the boil for 2 hours
  2. filtrationfiltered while hot, and the filtrate
  3. additionis poured into 100 parts of water
  4. filtrationThe precipitate which separates out is filtered off under suction
  5. washwashed with water
  6. customdried

Sources & evidence

ORD record
ord-31f6ebe5a1fe469f965c67295017ed80
Source dataset
uspto-grants-1993_04
Patent number
US05206375

Reaction notes

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