Hydrochloric Acid → HCID 13742395, compound

HRID 1591292Notes

Reaction equation

HRID 1591292 reaction equation
CN(C)C=[N:4][C:5]1[S:6][C:7]([N+:13]([O-:15])=[O:14])=[C:8]([Cl:12])[C:9]=1[C:10]#[N:11].Cl>C(O)C>[NH2:4][C:5]1[S:6][C:7]([N+:13]([O-:15])=[O:14])=[C:8]([Cl:12])[C:9]=1[C:10]#[N:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53781347HCID 53781347, compound

Product 1

HCID 13742395HCID 13742395, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 5.2 parts of N,N-dimethyl-N'-(4-chloro-3-cyano-5-nitrothien-2-yl)-formamidine, 50 parts of ethanol and 5 parts of concentrated hydrochloric acid is heated at the boil for 3 hours and then poured onto ice water. The precipitate is filtered off under suction, washed with water and dried. 3.2 parts (79% of theory) of 2-amino-4-chloro-3-cyano-5-nitrothiophene are obtained. Decomposition temperature: 227° C. (from o-dichlorobenzene).

Workup

  1. temperatureis heated at the boil for 3 hours
  2. additionpoured onto ice water
  3. filtrationThe precipitate is filtered off under suction
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-a7f6f9373dcd4264b907013ff5a7506f
Source dataset
uspto-grants-1993_04
Patent number
US05206375

Reaction notes

Loading…