Hydrochloric Acid → HCID 19766770, compound

Participants

Reaction Steps

A mixture of 6.1 parts of N,N-dimethyl-N'-(4-chloro-3-cyano-5-methylthien-2-yl)-formamidine, 50 parts of ethanol and 2 parts of concentrated hydrochloric acid is heated at the boil for 1 hour. Thereafter, the mixture is added to a dilute aqueous sodium acetate solution, and the precipitate is filtered off under suction and dried. 4 parts (86% of theory) of 2-amino-4-chloro-3-cyano-5-methylthiophene are obtained.

Provenance & Evidence