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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591327Generated: November 1, 2026

Methyl iodide → 1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-one

https://huagongshe.com/reaction/1591327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant1-(2,4-Difluorophenyl)-2-(3-pyridinyl)-ethanoneHCID 18956524—
Product1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-oneHCID 1895654173.6%

Reaction Steps

Methylation of the product of part (i) (5.0 g) with iodomethane (7.60 g) according to the method of Example 11(ii) gave the title compound as an oil (3.90 g) which was used directly in the next stage.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05206364
Source datasetuspto-grants-1993_04
ORD IDord-fb654f5d6f7d43dc8a492bf02a39af0c
Source noteuspto-grants-1993_04