HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → HCID 19025533, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid | HCID 10376046 | — |
| Reactant | 3-Amino-6-fluoro-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 19766186 | — |
| Product | HCID 19025533 | HCID 19025533 | — |
Reaction Steps
Prepared from 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) and the amine obtained in Step F by the procedure described in Example 1, Step F. 1H NMR (300 MHz, CDCl3): 1.36 (s,6H), 1.43 (s,9H), 1.91 (m,1H), 2.4-2.8 (m,3H), 3.18 (m,2H), 4.54 (m,1H), 5.18 (br s,1H), 6.66 (d,7 Hz,1H), 6.81 (d,8 Hz,1H), 6.94 (t,8 Hz,1H), 7.18 (m,1H), 7.71 (br s,1H). FAB-MS: calculated for C20H28FN3O4 393; found 394 (M+H,26%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05206235 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-7b22efc9259b48839f06ad97fc1072d0 |
| Source note | uspto-grants-1993_04 |