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HRID1591452

反应详情

EQUATION

反应方程式

HRID 1591452 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(CC(=O)O)NC(=O)OC(C)(C)C
HCID10376046

3-[(tert-Butoxycarbonyl)amino]-3-methylbutanoic acid

C10H19NO4

结构：NC1Sc2ccccc2NC1=O
HCID10797452

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(CC(=O)NC1Sc2ccccc2NC1=O)NC(=O)OC(C)(C)C
HCID19025720

未命名化合物

PROCEDURE

实验过程

Prepared from 2-amino-3,4-dihydro-3-oxo-2H-1,4-benzothiazine (Step A) and 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) by the procedure described in Example 1, Step F. 1H NMR (200 MHz, CD3OD): 1.26 (s,6H), 1.36 (s,9H), 2.47 (d,13 Hz,1H), 2.57 (d,13 Hz,1H), 5.52 (br s,1H), 6.31 (br s,1H), 7.00 (m,2H), 7.22 (m,2H). FAB-MS: calculated for C18H25N3O4S 379; found 380 (M+H,26%).